(S)-8-((5-(5-bromo-6-((S)-1-methoxyethyl)pyridin-3-yl)pyrimidin-2-yl)methyl)octahydropyrazino[2,1-c][1,4]oxazine

(7R,14R)-1-(difluoromethoxy)-10-fluoro-6,7-dihydro-11-[3-(1-hydroxy-1-methylethyl)-1-azetidinyl]-7,14-Methanobenzimidazo[1,2-b][2,5]benzodiazocin-5(14H)--one

2-((R)-6-((7R,14R)-1-(difluoromethoxy)-6-methyl-5-oxo-5,6,7,14-tetrahydro-7,14-methanobenzo[f]benzo[4,5]imidazo[1,2-a][1,4]diazocin-11-yl)-2,2-difluoro-3-hydroxy-2,3-dihydrofuro[3,2-b]pyridin-3-yl)acetonitrile

(1S,3s)-1-cyclopropyl-3-(5-((7R,14R)-1-(difluoromethoxy)-6-methyl-5-oxo-5,6,7,14-tetrahydro-7,14-methanobenzo[f]benzo[4,5]imidazo[1,2-a][1,4]diazocin-11-yl)pyrimidin-2-yl)-3-hydroxycyclobutanecarbonitrile

(7R,14R)-1-(difluoromethoxy)-11-((S)-4-hydroxy-2,2,4-trimethyl-3,4-dihydro-2H-pyrano[3,2-b]pyridin-7-yl)-6-methyl-6,7-dihydro-7,14-methanobenzo[f]benzo[4,5]imidazo[1,2-a][1,4]diazocin-5(14H)-one

(7R,14R)-1-(difluoromethoxy)-11-((S)-7-ethyl-7-hydroxy-6,7-dihydro-5H-cyclopenta[b]pyridin-3-yl)-6-methyl-6,7-dihydro-7,14-methanobenzo[f]benzo[4,5]imidazo[1,2-a][1,4]diazocin-5(14H)-one

(7R,14R)-1-(difluoromethoxy)-11-((S)-4-(fluoromethyl)-4-hydroxy-3,4-dihydro-2H-pyrano[3,2-b]pyridin-7-yl)-6-methyl-6,7-dihydro-7,14-methanobenzo[f]benzo[4,5]imidazo[1,2-a][1,4]diazocin-5(14H)-one

(7R,14R)-1-(difluoromethoxy)-11-((R)-3-ethyl-3-hydroxy-2,3-dihydrofuro[3,2-b]pyridin-6-yl)-6-methyl-6,7-dihydro-7,14-methanobenzo[f]benzo[4,5]imidazo[1,2-a][1,4]diazocin-5(14H)-one

(7R,14R)-1-(difluoromethoxy)-11-((R)-3-(fluoromethyl)-3-hydroxy-2,3-dihydrofuro[3,2-b]pyridin-6-yl)-6-methyl-6,7-dihydro-7,14-methanobenzo[f]benzo[4,5]imidazo[1,2-a][1,4]diazocin-5(14H)-one

(7R,14R)-11-[3-amino-2,3-dihydro-3-(1-propyn-1-yl)-furo[3,2-b]pyridin-6-yl]-1-(cyclopropylmethoxy)-6,7-dihydro-6-methyl-7,14-Methanobenzimidazo[1,2-b][2,5]benzodiazocin-5(14H)--one

(7R,14R)-11-[4-(diethylphosphinyl)-2-fluorophenyl]-1-(difluoromethoxy)-6,7-dihydro-7,14-Methanobenzimidazo[1,2-b][2,5]benzodiazocin-5(14H)--one

(S)-tert-butyl 4-((5-(5-bromo-6-(1-methoxyethyl)pyridin-3-yl)pyrimidin-2-yl)methyl)piperazine-1-carboxylate

(S)-tert-butyl 4-(2-(4-(5-bromo-6-(1-methoxyethyl)pyridin-3-yl)-1H-pyrazol-1-yl)ethyl)piperazine-1-carboxylate

(S)-tert-butyl 4-(3-(5-bromo-6-(1-methoxyethyl)pyridin-3-yl)isoxazol-5-yl)piperidine-1-carboxylate

(S)-tert-butyl 6-(5-bromo-6-(1-methoxyethyl)pyridin-3-yl)-1H-pyrrolo[3,4-c]pyridine-2(3H)-carboxylate

(S)-tert-butyl 3-(5-bromo-6-(1-methoxyethyl)pyridin-3-yl)-5H-pyrrolo[3,4-b]pyridine-6(7H)-carboxylate

(R)-tert-butyl 2-(3-(5-bromo-6-((S)-1-methoxyethyl)pyridin-3-yl)isoxazol-5-yl)pyrrolidine-1-carboxylate

(S)-tert-butyl 3-(4-(5-bromo-6-(1-methoxyethyl)pyridin-3-yl)-1H-pyrazol-1-yl)azetidine-1-carboxylate

(S)-tert-butyl 3-(3-(5-bromo-6-((S)-1-methoxyethyl)pyridin-3-yl)isoxazol-5-yl)pyrrolidine-1-carboxylate

(S)-tert-butyl 6-(5-bromo-6-(1-methoxyethyl)pyridin-3-yl)-3,4-dihydroisoquinoline-2(1H)-carboxylate

(S)-tert-butyl 4-(4-(5-bromo-6-(1-methoxyethyl)pyridin-3-yl)-1H-pyrazol-1-yl)piperidine-1-carboxylate